14 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Elevated Liver tests ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Elevated Liver tests ... child * Severe cases ... #HELLP #AFLP #obstetrics ... #hematology #diagnosis
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
abnormal liver tests ... in pregnancy - ... #transaminits #pregnancy ... #obgyn #obstetrics ... #hepatology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential Diagnosis ... K), H. pylori test ... thyroid function test ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... antiphospholipid syndrome - Pregnancy ... #Differential #Diagnosis ... #Framework #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in Pregnancy ... Cholestasis of Pregnancy ... features: Hemolysis, Thrombocytopenia ... #hepatology #obstetrics ... #differential #diagnosis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... hypersplenism and related thrombocytopenia ... Fatty liver of pregnancy ... #Differential #Diagnosis ... #causes #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Pregnancy) - Low ... Liver Function Tests ... #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... = nonspecific (nausea ... ) Differential Diagnosis ... #hepatology #obstetrics ... #obgyn #diagnosis
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... triad of MAHA + thrombocytopenia ... transplant, infection, pregnancy ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp