18 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Hemolysis #Hemolytic #Anemia ... #Workup #Hematology ... GrepMed Recommended Text
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... #Causes #Workup ... #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... Disorientation, vertigo Diagnostic ... test, TempTest ... #Urticaria #diagnosis ... #rheumatology #
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... Elevated Liver tests ... child * Severe cases ... #obstetrics #hematology ... #diagnosis #table
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... : • Liver disease ... • AIHA: warm, cold ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Liver Function Tests ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... #hematology #anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... anemiaCold ... Test: Donath-Landsteiner ... test #cold # ... #hematology #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Agglutination - Cold ... #Algorithm #workup ... #hematology #testing
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Elevated Liver tests ... child * Severe cases ... TTPHUS #HELLP #AFLP ... #Obstetrics #OBGyn ... #Hematology #Diagnosis