11 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Labs: • Alkaline ... • ALT & AST normal ... • Bilirubin - Normal ... bile ducts Differential ... #workup #hepatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Diagnosis Algorithm ... Lymphadenopathy #LAD ... Diagnosis #Algorithm ... #Causes #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
and Management Algorithm ... ±AKI Initial labs ... : CBC, BMP, Reticulocytes ... hemosiderin • PT/aPTT normal ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Infiltrative Labs ... - elevation Labs ... #hepatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Diagnosis Algorithm ... Drug-induced AIHA - Abnormal ... elliptocytosis - RBC ... Prosthetic heart valves ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... mechanical cardiac valve ... #Diagnosis #Algorithm ... #workup #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... bcr-able (+) ↑ WBC ... Amy Chung, MD, MSc ... Blood #Disorders #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... permanent alopecia Differential ... pneumonitis • Diffuse ... enteropathy, and diffuse ... Cytopenias • Cardiac valve
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... lymphadenopathy more diffuse ... Amy Chung, MD, MSc ... pathophysiology #Hematology ... #algorithm
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology