44 results
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... hemoglobin/hemosiderin, Hepatic ... hemosiderin • PT/aPTT normal ... #Differential #Diagnosis ... Management #Algorithm #hematology
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Approach to suspected Heparin-Induced ... Algorithm • "4 T's" clinical ... NephPrasad #Heparin ... Thrombocytopenia #HIT #hematology ... #diagnosis #4Ts
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... • Acute DIC - Septic ... Summary #table #comparison ... #diagnosis #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential Diagnosis ... Hepatic, Portal, ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding disorder Clinical ... Laboratory • Normal ... PT/INR • Normal ... VonWillebrand #Disease #Diagnosis ... #Hematology
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... K Antagonists, Heparin ... ISNeducation #Abnormal ... APTT #prolonged #diagnosis ... #hematology #evaluation
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Decreased Support Of Dermal ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... CK, normal biopsy ... splenomegaly • Hepatic ... management #treatment #rheumatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
imaging: Normal ... • Histology: Normal-mild ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... also arise in normal ... Differential Diagnosis ... #oncology #diagnosis ... #differential #hematology