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differential algorithm causes laboratory liver abnormal appearance aptt lesions management pathophysiology prolonged radiology aflp disorders hellp microangiopathy obstetrics platelet pregnancy
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Coagulation Tests ... - Prolonged PT ... and Prolonged PT ... #Laboratory #Hematology ... #Diagnosis #Workup
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
(INR), Normal PTT ... Prolonged PTT, Normal ... #Differential #Diagnosis ... Algorithm #Causes #Hematology ... #coagulation #disorders
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... Medications - Heparin ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Coagulation Cascade Mnemonic - PITT vs PET PITT (with an I) = Intrinsic = APTT
Coagulation Cascade ... E)= Extrinsic=PT ... @pinoygastro #Coagulation ... Mnemonic #PITT #PET #diagnosis ... #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... platelet aggregation PT ... using INR use PT ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... hemoglobin/hemosiderin, Hepatic ... hemosiderin • PT ... /aPTT normal • ... Management #Algorithm #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... - APTT < 1.5 x normal ... #diagnosis #causes ... treatment #management #hematology
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Step 1: Is the PT ... K Antagonists, Heparin ... Prolonging the PT ... APTT #prolonged #diagnosis ... #hematology #evaluation
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
an inhibitor of normal ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
- Differential Diagnosis ... Table • Thrombotic ... Metabolism-mediated TMA - Coagulation-mediated ... Microangiopathy #TMA #hematology ... #differential #diagnosis
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