37 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... APTT Step 1: Is ... K Antagonists, Heparin ... ISNeducation #Abnormal ... #diagnosis #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... hemoglobin/hemosiderin, Hepatic ... hemosiderin • PT/aPTT ... normal • DAT ... #Algorithm #hematology
Bullous pemphigoid and pemphigus vulgaris

Comparison Table via Physical Examination, Nikolsky Sign and Differential Diagnoses

#Diagnosis #Dermatology #Bullous
pemphigus vulgaris Comparison ... Table via Physical ... Diagnoses #Diagnosis ... #Dermatology #Bullous ... #Comparison #Table
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PTT, Normal PT ... , Normal PT (INR ... #PPT #PT #INR #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
PT/INR • Normal ... aPTT (prolonged ... factor VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... amyloidosis #Abnormal ... #Causes #diagnosis ... #differential # ... hematology #coagulation
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... and first-line treatment ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
INR < 2.3 - APTT ... < 1.5 x normal ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... #Causes #diagnosis ... #differential # ... hematology #coagulation
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Liver #Lesions #Hepatic ... POCUS #radiology #differential ... #diagnosis #comparison ... #table #appearance ... #hepatology