18 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... Medications - Heparin ... Alcohol, Viral hepatitis ... #table #comparison ... #diagnosis #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
CK, normal biopsy ... splenomegaly • Hepatic ... hepatomegaly, hepatitis ... #management #treatment ... #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management Summary ... marrow) -dys- (abnormal ... only curative treatment ... #Management #treatment ... #hematology #oncology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
imaging: Normal ... • Histology: Normal-mild ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... and Management Summary ... - CRP: Usually normal ... life-threatening • Treatment ... #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management Summary ... Diagnostic Criteria ... concentration in the normal ... #Management #Summary ... #treatment #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) - Summary ... • ALT & AST normal ... : • Viral hepatitis ... malignancies, Hepatic ... #workup #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
+ Bleeding Treatment ... - APTT < 1.5 x normal ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... +++ (Plt, Hb), Hepatic ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
Hepatic Encephalopathy ... Management Summary ... L-aspartate (LOLA), oral ... LizzieAbyMD #Hepatic ... #hepatology