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differential causes algorithm management abnormal aptt prolonged bruising dic disorders disseminated hodgkins intravascular laboratory lymphoma treatment afib anemia anticoagulation aplastic
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PT (INR) - Bleeding ... PT (INR) - No Bleeding ... #Differential #Diagnosis ... Algorithm #Causes #Hematology ... #coagulation #disorders
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Coagulation Tests ... - Prolonged PT ... and Prolonged PT ... #Laboratory #Hematology ... #Diagnosis #Workup
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... • Prolonged bleeding ... PT/INR • Normal ... VonWillebrand #Disease #Diagnosis ... #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Destruction • Abnormal ... #Bleeding #Bruising ... Algorithm #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... - APTT < 1.5 x normal ... #diagnosis #causes ... treatment #management #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... platelet aggregation PT ... using INR use PT ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... ) ABNORMAL PT ... PT/ABNORMAL PTT ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... - History of bleeding ... selected cases: INR/PT ... #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... intravascular coagulation ... #Causes #diagnosis ... #differential #hematology ... #coagulation
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis ... study (aPTT may be normal ... mild cases) • PT ... antigen (vWF:Ag) are normal ... Management #treatment #hematology
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