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mds myelodysplastic syndrome abscess aplastic apml arteritis bruising causes children classification crisis differentiation gca giantcell hepatology hodgkins liver lymphoma monoclonal
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... marrow) -dys- (abnormal ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... syndrome (MDS) (normal ... megakaryocytes and a normal ... #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
initiation • Differential ... Diagnosis: Infection ... 500 mg QD until normal ... #management #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Cryoglobulinemic, Hypo/normo-complementemic ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... blood cells appear normal ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... products that define normal ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... 50 in GCA, but normal ... systemic complaints- anemia ... them, but urgent rheumatology ... #Management
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
- Fanconi anaemia ... Platelet count normal ... Bruising #Causes #peds ... #pediatrics #diagnosis ... #differential #
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
endocarditis) - Portal ... liver #abscess #pediatrics ... #children #peds ... #differential # ... diagnosis #hepatology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
hypertension 3) Abnormal ... microangiopathic hemolytic anemia ... of arteries Management ... , add other BP meds ... #management
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