78 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Learning about thromboelastography (TEG).
- Tom Fadial
@thame

#Diagnosis #Hematology #Coagulation #Pharmacology #Thromboelastogram #TEG #Interpretation #Thromboelastography #Laboratory
#Diagnosis #Hematology ... #Coagulation #Pharmacology
TEG INTERPRETATION MADE EASY WITH WINE GLASSES

#Diagnosis #Pharmacology #Hematology #Coagulation #Thromboelastogram #TEG #Interpretation #WineGlasses #Mnemonic
#Diagnosis #Pharmacology ... #Hematology #Coagulation
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal ... Coagulation Tests ... #Algorithm #Coagulation ... #Abnormal #APTT ... #Laboratory #Hematology
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
numerals refer to coagulation ... #Hemostasis #Pathophysiology ... #Coagulation #Cascade ... #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Prolonged PT (INR), Normal ... Prolonged PTT, Normal ... Prolonged PTT, Normal ... Algorithm #Causes #Hematology ... #coagulation #disorders
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
an inhibitor of normal ... to have 50% of normal ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... Expected: Low (or normal ... consumption of coagulation ... Intravascular #Coagulation ... Scoring #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thrombocytopenia - Normal ... + Bleeding Treatment ... - APTT < 1.5 x normal ... #management #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
hemorrhage, while under-coagulation ... management #algorithm #pharmacology ... #treatment #medications ... decisionaid #cardiology #hematology