21 results
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Algorithm - Iron deficiency ... anemia - Anemia ... and/or folate deficiency ... disorder - TSH, LFTs ... Underproduction #Algorithm #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Microangiopathic Hemolytic Anemias ... • Early Iron Deficiency ... #Normocytic #Anemia ... Algorithm #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
• Dietary Deficiency ... Target Cells, Normal ... WBCs - Normal ... B12 and Folate Deficiency ... Algorithm #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
80 fL) • Iron Deficiency ... Chronic Disease Normal ... 100 fL) • B12 Deficiency ... • Folate Deficiency ... Algorithm #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Microcytic" • Iron deficiency ... some patients) Normal ... Megaloblastic: Vitamin B12 deficiency ... , Folate deficiency ... diagnosis #causes #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... RBC Production - Normal ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... Algorithm #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... RBC>13 • Iron Deficiency ... Malabsorption, Dietary Deficiency ... TlBC > 18% • Anemia ... Algorithm #Causes #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• AIH • A1AT deficiency ... disease US — Normal ... • Others #LFTs ... #Hepatology #LiverEnzymes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... syndrome (MDS) (normal ... megakaryocytes and a normal ... #oncology #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Drug-induced AIHA - Abnormal ... Defects • G6PD deficiency ... • PK deficiency ... immune-complex hemolytic anemia ... Algorithm #Causes #Hematology