25 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Levels: > 50x normal ... > 20x normal ... , Toxic Hepatitis ... Liver #Injury #hepatology ... #LFTs #transaminitis
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Vascular: Budd-chiari syndrome ... , Portal vein thrombosis ... • Autoimmune hepatitis ... Transaminases #hepatitis ... Diagnosis #causes #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
disease US — Normal ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... - If both are normal ... • Gilbert's syndrome ... #differential #Hepatology ... transaminitis #LFTs
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
in Cirrhosis Portal ... ) Budd Chiari Syndrome ... Circulation #Disorders #Hepatology ... Gastroenterology #diagnosis #Management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... marrow) -dys- (abnormal ... Myelodysplastic #Syndrome ... #treatment #hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Portal Hypertension ... and hepatorenal syndrome ... • Budd Chiari syndrome ... Cirrhosis/acute hepatitis ... Diagnosis #causes #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites Normal ... - Budd-Chiari syndrome ... - Alcoholic hepatitis ... - Nephrotic syndrome ... #differential #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... (>10^6 IU/mL), normal ... liver failure #HepatitisB ... #Indications #management ... #hepatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Symptoms (DRESS) Syndrome ... topical steroid +/- oral ... count daily • LFTs ... #Treatment #Management ... #dermatology