29 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
findings • Anterior Knee ... with possible symptoms ... Patellofemoral #Syndrome #pathophysiology ... #diagnosis #signs ... #symptoms #msk
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
and Symptoms ... of motion • Abnormal ... Radiculopathy #MSK ... #diagnosis #signs ... #symptoms #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Popliteal (Baker’s) Cyst: Pathogenesis and clinical findings
 • Idiopathic
 • Meniscal Lesions
 • Osteoarthritis
 • Rheumatoid
intra-articular knee ... Popliteal #BakersCyst #MSK ... #pathophysiology ... #signs #symptoms ... #diagnosis
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... Areflexia (loss of normal ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... Aneurysmal bone cyst ... - Synovium - Oral ... #msk #physicalexam
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Valgus position of knee ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis ... #msk
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
is thought to cause ... is thought to cause ... Schizophrenia #pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... skin (16-32%): lupus ... anterior/posterior MSK ... ), liver (pain/abnormal ... #Management #Signs