38 results
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... splenomegaly, abnormal ... neurology, back ... #Child #Peds #Pediatrics ... #Diagnosis
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
in blood flow caused ... Depends on the cause ... Pulmonary embolism ... : Normal cardiac ... #criticalcare #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Idiopathic • Normal ... With associated pulmonary ... #differential #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... , and CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
a patient with portal ... other obvious causes ... m/s • Other signs ... pressure < 15mmHg TREATMENT ... - Mechanism: causes
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... 500 mg QD until normal ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... • ALT & AST normal ... #workup #hepatology