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diagnosis hematology differential neurology pediatrics cardiology algorithm rheumatology signs syndromes barre dermatology dress guillain hepatology hepatopulmonary infectiousdiseases lung mds myelodysplastic
Tetralogy of Fallot Summary • Anatomy • Incidence • Pathophysiology • Presentation • Common Variants •
• Incidence • Pathophysiology ... Associated Genetic Syndromes ... Fallot #diagnosis #management ... #cardiology #peds ... #pediatrics #treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... only curative treatment ... #treatment #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Pathophysiology ... Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms ... 500 mg QD until normal ... #hematology #oncology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
of Tumor Lysis Syndrome ... upper limit of normal ... #TumorLysis #Syndrome ... TLS #diagnosis #management ... #oncology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... sleep apnea, cor pulmonale ... #genetics #pathophysiology ... #peds #pediatrics
BRASH Syndrome B - Bradycardia R - Renal failure A - AV nodal blockade S - Shock H - Hyperkalemia Typical ECG
BRASH Syndrome ... • Aggressive treatment ... balanced fluids" > normal ... #diagnosis #management ... #pathophysiology
Management of Serotonin Syndrome Identify and stop all serotoninergic medications • Avoid inadvertent Rx of serotoninergic meds
Syndrome Identify ... serotoninergic meds ... antagonist • Oral ... then 2 mg q2h if symptoms ... #Management #treatment
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation
Treatment Schema ... mercaptopurine, Weekly oral ... #timeline #oncology ... #pediatrics #peds ... #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... : • Pathophysiology ... TLS #diagnosis #management
Medical Treatment Algorithm for Chronic Obstructive Pulmonary Disease Initial medical treatment of chronic obstructive pulmonary disease (COPD)
Chronic Obstructive Pulmonary ... of obstruction, symptom ... control persistent symptoms ... outpatient setting with oral ... #Algorithm #Management
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