18 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... - CRP: Usually normal ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Idiopathic • Normal ... With associated pulmonary ... Glomerulonephritis #Vasculitis #differential
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... #diagnosis #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... CK, normal biopsy ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
study (aPTT may be normal ... in mild cases) ... antigen (vWF:Ag) are normal ... Avoid meds that ... #treatment #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Autoimmune Vasculitis (lupus ... Diagnosis #Algorithm #Causes ... #dermatology #physicalexam
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
- Switch to oral ... Lung Abscess Differential ... Lung #Abscess #pulmonary ... #differential # ... causes #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
a patient with portal ... other obvious causes ... pressure < 15mmHg TREATMENT ... Hypertension #diagnosis #management ... #hepatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
lung disease Caused ... cirrhosis • Intra-pulmonary ... perfusion scanning or pulmonary ... ) on room air Treatment ... #treatment #hepatology