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RHABDOMYOLYSIS • Characterized by skeletal muscle breakdown & necrosis. • Elevated Creatine kinase (CK) hallmark of rhabdomyolysis. • Defined based
Creatine kinase (CK ... Defined based on CK ... • Half-life of CK ... peaks in 3 days, & normalizes ... and cefdinir #CK
INR Chart - International Normalized Ratio #INR #International #Normalized #Ratio #Range #Laboratory
International Normalized ... International #Normalized
Creatine kinase (CK) is an intracellular enzyme present in skeletal muscle, myocardium & brain; smaller amounts
Creatine kinase (CK ... CK may increase ... creatine kinase (CK ... CK functions as ... first 3 days, and normalizes
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase - Causes ... of Elevated CK ... Levels Acute CK ... Subacute to Chronic Causes ... Kinase #Elevated #CK
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Normal CK ... Weakness, Incr CK ... Myopathy (Also caused ... therapy), Normal CK
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
weakness • Elevated CK ... rash • Elevated CK ... Elevated ESR, Normal CK ... mildly elevated CK ... Myositis: elevated CK
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Clotting test normalizes ... test does not normalize
Drugs Causing Acute Pancreatitis Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... out other common causes ... Class II: Cases ... and atleast4 case ... #Pancreatitis #Causes
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm With Sensory Changes:
Causes of Peripheral ... involvement, elevated CK ... Diagnosis #Algorithm #Causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
osmolarity If cause ... Rhabdo-myolysis: CK ... syndrome: troponin, CK-MB ... Diagnosis #nephrology #causes
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