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diagnosis differential algorithm clinical management hematology workup pocus causes hepatology ultrasound microscopy pathophysiology treatment nephrology anemia blood cardiology pulmonary syndrome
Erythropoiesis (RBC Production and Maturation) Pluripotent hematopoietic stem cell → Proerythroblast (a.k.a. pronormoblast) → Erythroblast (a.k.a. normoblast)
Erythropoiesis (RBC ... Erythroblast (a.k.a. normoblast ... Erythropoiesis #RBC
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
blood cells, aka normoblasts ... polychromatophilic normoblast ... are orthochromic normoblasts ... – orthochromic normoblast ... Smear #Nucleated #RBCs
Urine Microscopy and Casts - Image Atlas Key - Squamous Epithelial Casts - Transitional Epithelial Cells - Renal Tubular
- Monomorphic RBCs ... - Dysmorphic RBCs ... Granular Casts - WBC ... Cast - RBC Cast
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
/ Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Thalassemia • RBC ... Disorder • RBC
Urinalysis Interpretation (UA) Bacteria, Leukocyte esterase, WBC, Nitrite, RBC, Epithelial cells, pH #Diagnosis #Urinalysis #Interpretation #Analysis
Leukocyte esterase, WBC ... , Nitrite, RBC,
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 The differential diagnosis for an elevated MCHC (mean corpuscular hemoglobin concentration) includes: Conditions with Abnormal RBCs: •
with Abnormal RBCs ... : • Abnormal RBC ... Xerocytosis • RBC
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
directed donations) - RBC ... WBC and platelets ... Hct of 70-80% - RBC ... plasma, a few RBC ... ofplasma, a few RBC
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
glomerular hematuria (RBC ... or dysmorphic RBCs
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Macrocytes, Normal RBCs ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... ) - Abnormal RBCs
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... 3) Internal (RBC ... Smear ↑ abnormal RBCs
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