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diagnosis management hematology differential clinical algorithm microscopy anemia abcs blood causes nephrology smear urine rbc pathophysiology treatment workup hemolytic path
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
blood cells, aka normoblasts ... polychromatophilic normoblast ... are orthochromic normoblasts ... – orthochromic normoblast ... Smear #Nucleated #RBCs
Erythropoiesis (RBC Production and Maturation) Pluripotent hematopoietic stem cell → Proerythroblast (a.k.a. pronormoblast) → Erythroblast (a.k.a. normoblast)
Erythropoiesis (RBC ... Erythroblast (a.k.a. normoblast ... Erythropoiesis #RBC
Urine Microscopy and Casts - Image Atlas Key - Squamous Epithelial Casts - Transitional Epithelial Cells - Renal Tubular
Hyaline Cast - WBCs ... - Monomorphic RBCs ... - Dysmorphic RBCs ... - WBC Cast - RBC
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Normal/lncreased WBCs ... Macrocytes, Normal RBCs ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... ) - Abnormal RBCs
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Urinalysis >3 RBCs ... of UTI, urine WBCs ... (proteinuria, RBC ... casts, dysmorphic RBCs
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
/ Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Thalassemia • RBC ... Disorder • RBC
Pathophysiology of Hemolytic Anemia - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects) -
- Defects in RBC ... - Defects in RBC ... Defects in the RBC's
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
glomerular hematuria (RBC ... or dysmorphic RBCs
The differential diagnosis for an elevated MCHC (mean corpuscular hemoglobin concentration) includes: Conditions with Abnormal RBCs: •
with Abnormal RBCs ... : • Abnormal RBC ... Xerocytosis • RBC
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
red blood cells (RBCs ... serum due to the RBCs ... Smear #Microscopy #RBC
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