43 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... *Always do arthrocentesis ... #Joint #Pain #MSK ... #rheumatology #
Arthrocentesis - Joint Fluid Analysis

Effusion Characteristics (Color, Clarity, WCC, PMN, Crystals, Bacteria) by Disease Process: 
OA,
Arthrocentesis - ... Joint Fluid Analysis ... Disease Process: OA ... #Differential #Arthrocentesis ... #Joint #Syonvial
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Osteoarthritis (OA ... Stimulation of joint ... subchondral bone -> Pain ... nociceptors -> Pain ... Osteoarthritis #OA
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders ... Osteoarthritis (OA ... Polyarthritis • Systemic Lupus ... with Systemic Lupus ... @AmyChung #Joint
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... Anti-retrovirals, Gemcitabine Lupus ... Diffuse muscle pain ... uncommon 5-15% of lupus ... diagnosis #comparison #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... lesions • Discoid lupus ... #dermatology #joint ... #pain #skin #rashes ... differential #diagnosis #rheumatology
Arthritis of the Hand - Arthritis Patterns

Osteoarthritis:
• Osteoarthritis of the hand usually involves the DIP and
the DIP and PIP joints ... the PIP and MCP joints ... but not the DIP joints ... DIP + 1st CMC = OA ... hand #diagnosis #rheumatology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Inflammatory Joint ... nociceptors -> Pain ... painful swelling -> Pain ... Rheumatoid arthritis, Lupus ... -> Pain with motion
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... phenomenon (20%) Joints ... Arthritis in small joints ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Inflammatory Joint ... Pain - Differential ... Oligoarticular (1-4 joints ... POLYARTICULAR (>4 joints ... Arthritis • Systemic Lupus