35 results
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential Diagnosis ... Non-Malignant • Amyloidosis ... myelofibrosis) Inflammatory ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Acute or Chronic Inflammatory ... disorders • Celiac disease ... effect following treatment ... #Differential #Diagnosis
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
- Differential Diagnosis ... Hemochromatosis • Wilson's Disease ... • Amyloidosis ... Schistosomiasis Inflammatory ... Algorithm #Causes #Hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Rebound effect from treatment ... myelosuppressive agents • Inflammatory ... Vasculitides, IBD, Celiac disease ... #Differential #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... permeability Diagnosis ... : • Inflammatory ... #cerebritis #diagnosis
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... (AOSD) Rare inflammatory ... synovitis (40%) Treatment ... #AOSD #rheumatology ... #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... production of pro-inflammatory ... • Autoimmune diseases ... Unknown cause Treatment ... #management #treatment
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... but elevated as disease ... malignancies, Hepatic amyloidosis ... , IgG4 related disease ... #workup #hepatology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... Disease • Swelling ... #Degenerative #Comparison ... JointDisease #JointPain #Diagnosis ... #pathophysiology
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
Classification Types - Pathophysiology ... Comparison Obstructive ... and release of inflammatory ... advanced valvular disease ... #diagnosis #classification