37 results
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
• The disease ... present with a red eye ... gradient bows iris ... damage & blindness Signs ... ClosedAngle #Glaucoma #pathophysiology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... - High serum CRP ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
pelvic pain • Eyes ... layer (uvea): iris ... ReactiveArthritis #pathophysiology ... #diagnosis #signs ... #symptoms
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... detachment • Red Eye ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... Males=Females SIGNS ... /SYMPTOMS: • Acute ... steroids for severe disease ... #management #pulmonary
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
/ Symptoms: - ... Keratoconjunctivitis sicca (Dry eyes ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... CMC_IM #Potts #Disease
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... Increased ESR and CRP ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Blood: Anemia Eyes ... interstitial lung disease ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms ... #diagnosis #ExtraArticular
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... increase in CD4+ cells ... pericarditis, peritoneal disease ... weeks for most OI ... #Management