29 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... • Tumor lysis syndrome ... ) CLL Symptoms: ... Transformation: • Complication ... Hematology #Oncology #Diagnosis
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
cells -> Mutagenic ... / Symptoms / Complications ... detachment • Red Eye ... ophthalmology #diagnosis ... #signs #symptoms
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Diagnosis: • ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... CRP Neuronal cell ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
present with a red eye ... and are acutely ill ... gradient bows iris ... damage & blindness Signs ... / Symptoms / Complications
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
pain/pain upon eye ... pain • Extra-CNS complications ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... Consider stem cell ... neutropenic fever) Complications ... #management #treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... increase in CD4+ cells ... weeks for most OI ... #Inflammatory #Syndrome ... #Management
Psoriatic Arthritis: Complications

 • Ocular - Inflammation of middle layer of the eye (the uvea, which
middle layer of the eye ... which includes the iris ... pathophysiology #diagnosis ... #signs #symptoms ... #Complications
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... thrombocytopenia Complications ... hematology #hemeonc #diagnosis ... #management