15 results
hematology rheumatology acute differential manifestations oncology ophthalmology vasculitis ankylosingspondylitis apml chronic closedangle differentiation extraarticular glaucoma henochscholeinpurpura hsp iga immune inflammatory
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
/ Symptoms / Complications ... detachment • Red Eye ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Diagnosis: • ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
B and CD-4+ T cells ... CRP Neuronal cell ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
and are acutely ill ... gradient bows iris ... damage & blindness Signs ... / Symptoms / Complications ... ClosedAngle #Glaucoma #pathophysiology
Psoriatic Arthritis: Complications • Ocular - Inflammation of middle layer of the eye (the uvea, which
middle layer of the eye ... which includes the iris ... PsoriaticArthritis #pathophysiology ... #diagnosis #signs ... #symptoms #Complications
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis of tumor cells ... #TLS #diagnosis ... #management #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... increase in CD4+ cells ... weeks for most OI ... #Inflammatory #Syndrome ... #Management
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... UV light Incr cell ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... #Management #Signs
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... • Induce blast cell ... : >3 symptoms, or ... #management #hematology
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