22 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Complications: MAS ... hepatitis • Pulmonary ... #Disease #diagnosis ... #management #treatment
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... #AdultOnset #Stills ... #Disease #AOSD ... #management #treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #onset #Stills
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
ROM +/- fever, chills ... osteomyelitis, trauma ... necrosis, Lyme disease ... Treatment: admission ... washout • Healthy Adults
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... arthritis (sJIA) • Adult-onset ... Still disease ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
More common in adults ... Culture & GS, PCR Treatment ... : • Severe Disease ... #management #treatment ... #infectiousdiseases
Rhodococcus - Microbiology Overview

Microbiology:
 • Facultative, intracellular, nonmotile, non-spore-forming
 • Aerobic acid-fast gram-positive coccobacilli
 • Produces
Transmission (Zoonotic disease ... inoculation due to trauma ... Diagnosis Treatment ... #Microbiology #diagnosis ... #treatment #pulmonary
Facial Swelling - Differential Diagnosis Framework for Facial Edema

Infectious:
	• Dental abscess
	• Ludwig's angina
	• Vincent's angina
	• Cellulitis
	•
- Differential Diagnosis ... polymyositis • Adult-onset ... Still's disease ... : • Morbihan disease ... #Differential #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... Unknown cause Treatment ... #management #treatment
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Fevers and/or chills ... Connective tissue diseases ... , in advanced disease ... is abnormal in adults ... mycobacteria Treatment