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rheumatology differential treatment systemic causes erythematosus lupus signs algorithm arthritis chronic oncology stills vasculitis activation adultonset ana antibodies antinuclear aosd
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... hepatitis • Pulmonary ... #diagnosis #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
& renal involvement ... block • Sjogren syndrome ... #Summary #diagnosis ... #rheumatology # ... management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... Still disease ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
33% of healthy adults ... context of other symptoms ... ), Sjogren's Syndrome ... , Interstitial Pulmonary ... #diagnosis #differential
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... endocarditis • Trauma ... discoloration) • Chronic renal ... • Nephrotic syndrome ... #Differential #Diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... or serologies + symptoms ... #Renal #Syndromes ... #management #treatment
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Metabolic • Renal ... Neoplastic / Hematologic ... Arthritis • SLE ... Disease Neurologic ... Chronic Fatigue Syndrome
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Epidemiology: • Young adults ... Oral aphthae : SLE ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Facial Swelling - Differential Diagnosis Framework for Facial Edema Infectious: • Dental abscess • Ludwig's angina • Vincent's angina • Cellulitis •
- Differential Diagnosis ... Autoimmune: • SLE ... polymyositis • Adult-onset ... Still's disease ... Subcutaneous emphysema Renal
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... Abdominal pain (20%) Renal ... disease (30%): ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
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