38 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... (MAS) Classified ... arthritis (sJIA) • Adult-onset ... #Diagnosis #Management ... #Hematology #Rheumatology
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... Rheumatoid Nodules, Pulmonary ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
arterial HTN) • Renal ... : scleroderma renal ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... or serologies + symptoms ... #Renal #Syndromes ... #management #treatment
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... • Burr cells - Renal ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... Anaphylaxis, Acute Renal ... #management #hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease & renal ... block • Sjogren syndrome ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Demyelinating syndromes ... Abdominal pain (20%) Renal ... erythematosus #signs #symptoms ... #diagnosis #rheumatology