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differential hematology disease nephrology rhabdomyolysis activation adultonset capillary clarksons coagulation dic differentiation disseminated diuresis diuretics emergencies excretion immune inflammatory intravascular
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... Anaphylaxis, Acute Renal ... #APML #diagnosis ... #management #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... and Management ... Summary Trauma ... iniury, Compartment syndrome ... #causes #treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... Goodpasture's cause ... #Renal #Syndromes ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... arthritis (sJIA) • Adult-onset ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Framework and Management ... Summary Causes ... Rhabdomyolysis: • Trauma ... #Management #causes
Orthopedic Emergencies Compartment Syndrome • An increase in compartment pressure to the point where tissue perfusion is
• Syndrome caused ... fractures in young adults ... • Diagnosis: ... H/O antecedent trauma ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Recent history of trauma ... Bleeding (64%) • Renal ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Diagnosis of ... irrigation • Management ... Torsemide) • Acute pulmonary ... Kidney stones caused ... Tolvaptan) • Treatment
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... 150 published cases ... filling +++ (risk of pulmonary ... #diagnosis #management ... #rheumatology
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