198 results
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Lupusreference #TMAs ... Erythematosus #SLE ... #hematology #rheumatology ... #differential #diagnosis
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Microangiopathy - TMAs ... MAHAs are due to TMAs ... triad of MAHA + thrombocytopenia ... catastrophic APS, SRC, SLE ... #hematology #diagnosis
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... first-line treatment ... Microangiopathy #thrombocytopenic ... #Comparison #Diagnosis ... #Table #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic ... Purpura (TTP) Diagnosis ... soon as TTP is diagnosed ... TTP Thrombotic #Thrombocytopenic ... #rheumatology #
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Autoimmune • ITP • SLE ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Heparin Induced Thrombocytopenia (HIT) - Likelihood, Diagnosis and Management
 - HIT Suspected
 - Calculate 4T Score
Heparin Induced Thrombocytopenia ... - Likelihood, Diagnosis ... and Management ... #Algorithm #Diagnosis ... #Management #Hematology
Hypereosinophilia (HE) Summary

 • Definition
 • When to Suspect?
 • A Partial Classification of Hypereosinophilia
 •
• A Partial Classification ... Hypereosinophilia • Diagnostic ... Presentations • Treatment ... Hypereosinophilia #HE #hematology ... #diagnosis #management
Algorithm for diagnosis of familial thrombocytopenia. Platelet size, best determined by review of the peripheral smear,
Algorithm for diagnosis ... of familial thrombocytopenia ... available measurement and ... #Diagnosis #Hematology ... #Familial #Thrombocytopenia
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus [SLE ... thrombocytopenia ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... - Autoimmune: SLE ... #Differential #Diagnosis ... #Framework #hematology