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diagnosis lysis oncology syndrome blood cardiomyopathy differential emergencies gammopathy hemeonc hfpef hypoxemia hypoxia leukostasis mgrs monoclonal obgyn oncologic peripartum ppcm
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... only if EKG changes ... Walid Malki, MD, MS ... Lysis #Syndrome #TLS ... #oncology #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... hydration - Hyperkalemia ... unless worrisome EKG ... #diagnosis #management ... #hematology
Hypoxemia / Hypoxia - Rapid Response Management Algorithm Stridor - Upper airway pathology: • Anaphylaxis • Foreign
Extrinsic compression (e.g ... ., hematoma, tumor ... CNS depression (e.g ... Neuromuscular disorders (e.g ... wall compliance (e.g
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... (tumor-lysis syndrome ... ): - Hematologic ... q8 h TLS labs, aggressive ... plasmapheresis Hypercalcemia
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
non-organized (e.g ... or no deposits (e.g ... Kidneys • Low Tumor ... Burden, High Toxicity ... Amyloid formation (e.g
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... High mortality. ... Hypocalcemia, Hyperkalemia ... Transfusions #diagnosis #management ... #hematology #reactions
HFpEF and CAD Management Algorithm 1. Consider revascularization based on current guidelines for CAD and HFpEF* 2. Statins:
HFpEF and CAD Management ... current guidelines (eg ... fluid status (hypervolemia ... #Management #Algorithm ... #cardiology
Peripartum Cardiomyopathy (PPCM) What is PPCM? • A form of acute systolic heart failure that develops late in
of pregnancy (e.g ... Genetic variants (e.g ... deficiencies (e.g ... Consider biomarkers (e.g ... recognition and management
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