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diagnosis differential causes anemia macrocytic management carcinoma chronic daytime electrophoresis elevatedmcv erythrocytosis excessive indications leukostasis lysis macrocytosis microcytic nephrology polycythemia
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Differential Diagnosis Algorithm ... Liver Failure • Hypercalcemia ... Neoplastic / Hematologic ... • Drug Abuse (e.g ... Syndrome #Chronic
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm Insufficient Sleep • Poor Sleep Hygiene • Insomnia
Sleep Deprivation (Eg ... Shift Work) Sleep ... • Medications (Eg ... • Drug Abuse (Eg ... Excessive #Daytime #Fatigue
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
Weight loss, fatigue ... Budd Chiari syndrome ... Hypercalcemia 4 ... Recombinant cytokines (e.g ... kinase inhibitors (e.g
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Differential Diagnosis Algorithm ... poisoning, OSA/OHS ... Paraneoplastic (e.g ... ., RCC, HCC, uterine ... #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic Algorithm ... (MCV): Average RBC ... of substrate (e.g ... #Diagnosis #Workup ... #Hematology #Microcytic
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... • Fanconi's syndrome ... sediment - WBC/RBC ... Protein deposition (eg ... Amyloidosis)
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
macroglobulinemia, primary amyloidosis ... suspected • Hypercalcemia ... possible malignancy (e.g ... associated weight loss, fatigue ... Electrophoresis #SPEP #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... Neutrophils - Low RBC ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Causes #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... : - Neuro: AMS ... hydration - Hyperkalemia ... unless worrisome EKG ... diagnosis #management #hematology
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