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differential workup ana anemia antinuclear nuclear patterns rheumatology testing algorithm aplastic cytoplasmic heon hypereosinophilia leukemia macrocytic management microcytic neoplastic neutropenia
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... treatment - Maternal antibody ... replacing the BM ... replacing the BM-common ... #causes #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... or if a primary hematologic ... When do you do a BM ... #Differential #Diagnosis ... #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in bone marrow (BM ... ) ablative disorders ... under 2%, then BM ... #Workup #Hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... NXP-2 (MORC3 or MJ ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
Exclusion of frequent causes ... - Myelogram/BM ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... NXP-2 (MORC3 or MJ ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
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