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algorithm transaminitis causes obstetrics hepatitis pathophysiology abnormal aflp ascites enzymes gastroenterology hepatocellular hypertension management obgyn saag abscess acute albumin alkaline
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... more specific for hepatic ... #differential # ... hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Differential Diagnosis ... (Drug-induced liver ... ) • Non-hepatic ... Diagnosis #hepatology
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... tests in pregnancy ... Hepatocellular Pattern #LFTs ... obgyn #obstetrics #hepatology ... #diagnosis #differential
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Injury - Differential ... - Liver Parenchyma ... Artery: Shock Liver ... #Injury #Differential
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... : Liver Injury ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... Hemolysis, Elevated Liver ... features: Liver ... BrighamChiefs #Liver ... #diagnosis #icp
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... Chronic - ongoing ↑ LFTs ... or symptoms of liver ... Drug #induced #Liver ... #differential #
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Injury: • Hepatic ... melanoma, myeloma • Pregnancy ... #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... #Patterns #Liver ... #Injury #hepatology ... #differential # ... diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... replaced by non-hepatic ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
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