17 results
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... #Laboratory #Metabolism ... AlkPhos #Bilirubin #Hepatology ... Pathophysiology #Diagnosis ... #LFTs
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... #Diagnosis #hepatology ... Transaminitis #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... disease: > 2 ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... Idiosyncratic #differential ... gastroenterology #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Defects, Drugs, Liver ... Hypophostphatemia Laboratory ... #Diagnosis #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
disease; AST, aspartate ... disease; T2DM, ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential #
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... disease (Wilson ... Presence of atypical laboratory ... #diagnosis #Alcoholic ... Hepatitis #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... disease (Wilson ... Presence of atypical laboratory ... Autoimmune #Hepatitis #Diagnosis ... #Hepatology #AIH
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... disease, decrease ... gastric bypass), LFT ... (liver disease) ... #Workup #hematology