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diagnosis hematology hemophagocytic hlh lymphohistiocytosis treatment abnormal algorithm arteritis behcet candida candidemia candidiasis coccidioides coccidioidomycosis differential disease enzymes fever fungemia
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... the respective fungal ... thin smear • Signs ... duplex or CTA • Liver ... Liver biopsy •
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... response to abnormal liver ... derangement of liver ... symptoms/signs ... the pattern of liver
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Candidemia Workup and Management ... or TEE unless clinical ... workup dictated by symptoms ... Consider: Spine, CNS, liver ... candidiasis #treatment #fungal
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Diagnosis: HLH signs ... and symptoms can ... lymph node, or liver ... Lymphohistiocytosis #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... inhibitors • Uveitis- Ophthalmology ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... has five major clinical ... Mississippi and Ohio River ... stain of clinical ... #Diagnosis #Management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... renal failure Clinical ... heart (2-5%), liver ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... them, but urgent rheumatology ... required +/- prompt ophthalmology ... #Management
Coccidioidomycosis (Coccidioides): Valley Fever - Summary Sheet • Morphology • Geography, Reservoir and Mode of Transmission
disseminated disease • Clinical ... self-limiting respiratory symptoms ... , eyes, heart, liver ... Diagnosis • Management ... #summary #fungal
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Clinical Presentation ... • Common Signs ... and Symptoms: ... - Elevated liver ... #Hematology #HemeOnc
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