15 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty ... Liver of Pregnancy ... (AFLP) Three syndromes ... Hemolysis, Elevated Liver ... #obstetrics #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Three syndromes ... Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... coagulation defects and liver ... Obstetrics #OBGyn #Hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Fatty Liver of ... Pregnancy (AFLP) ... features: Liver ... #hepatology #obstetrics
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... hepatocytes → Liver ... #Fatty #Liver # ... Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... vein: Budd-chiari syndrome ... melanoma, myeloma • Pregnancy ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Liver Failure ( ... ALF): • Liver ... • Gilbert's syndrome ... #differential #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Hepatocellular - Liver ... obstruction, HELLP Syndrome ... Artery: Shock Liver ... #algorithm #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... sarcoidosis) • Liver ... metastasis • Fatty liver ... of pregnancy ... Diagnosis #causes #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... fibrosis - Acute ... fatty liver of ... pregnancy 3. ... #differential #hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Findings in Hepatic / Liver ... liver failure; ... hepatocytes; in chronic liver ... has exhausted liver ... LiverFailure #Hepatic #Hepatology