59 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential ... Diagnosis Inadequate ... • Osmotic diuresis ... #nephrology #sodium
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
- Osmotic diuretic ... , Loop diuretics ... Postobstructive diuresis ... Classification #Features #Diagnosis ... Comparison #Table #Nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... • Euvolemic (Low ... , osmotic (solute ... #Differential # ... #Algorithm #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
- Differential ... administration • Osmotic ... diuresis (see Polyuria ... mannitol, glucosuria Low ... #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... - Differential ... Diagnosis Algorithm ... alkalosis, Ketonuria, Osmotic ... #Causes #nephrology
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Hyponatremia Correction ... Overcorrection of Hyponatremia ... → Osmotic Demyelination ... 3cc/kg/h, loop diuretics ... rate #management #nephrology
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
Diagnosis Excess ... Solute (a.k.a. osmotic ... diuresis): • ... • Central Dl (Low ... #nephrology
Increased Urination - Differential Diagnosis Framework - Increased Volume / Frequency
 • Increased osmotic load (Increased
Increased Urination - Differential ... Diagnosis Framework ... • Increased osmotic ... urine (usually low ... Increased intake (low
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Loop and thiazide diuretics ... Hypokalemia - Osmotic ... diuresis - ... Hypomagnesemia #Differential ... #Diagnosis #Low
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... thiazide-like diuretics ... , Osmotic diuresis ... Hypokalemia #Causes #differential ... #diagnosis #nephrology