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diagnosis differential management pharmacology causes algorithm hypernatremia hyponatremia medications pathophysiology sodium nephron neurology polyuria table diabetes endocrinology hypomagnesemia siadh sites
Diuretics sites of action on the nephron 1) Acetazolamide (carbonic anhydrase inhibitor) 2) Osmotic diuretics (e.g. mannitol) 3) Loop
Diuretics sites ... of action on the ... inhibitor) 2) Osmotic ... #pharmacology #nephrology ... medications #sites #action
Nephron Pathophysiology - Diuretic Sites of Action Diuretics 1) Acetazolamide/canagliflozin 2) Osmotic agents (mannitol, urearetics) 3) Loop agents (eg, furosemide) 4)
Sites of Action ... Diuretics 1) ... canagliflozin 2) Osmotic ... #Sites #Action ... #nephrology #pharmacology
Hormones Acting on the Nephron - Diuretics and Their Site of Action 1) Acetazolamide 2) Osmotic
Hormones Acting ... Their Site of Action ... Acetazolamide 2) Osmotic ... Diuretics (e.g. ... Pathophysiology #Nephrology
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Summary of Diuretic ... , Mechanism of Action ... • Triamterene OSMOTIC ... DIURETICS • Mannitol ... summary #table #nephrology
Causes of Hypernatremia - Differential Diagnosis Inadequate water intake: • Lack of access to water Extrarenal hypotonic fluid
concentrating defect: • Diuretics ... • Osmotic diuresis ... Diagnosis #Causes #nephrology
Hypernatremia Classification and Features According to Volume Status - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
hypernatremia - Osmotic ... diuretic, Loop ... diuretics, Postobstructive ... diuresis - Extrarenal ... Comparison #Table #Nephrology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... , nasogastric suction ... thiazide-like diuretics ... , Osmotic diuresis ... differential #diagnosis #nephrology
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Methazolamide Osmotic ... diuretics: • ... #Pharmacology #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
• Hypovolemic: Diuretics ... , osmotic (solute ... ) diuresis • Euvolemic ... Workup #Algorithm #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Diuretics and Agents ... periodic paralysis Osmotic ... the Nonspecific Cation ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
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