22 results
management differential hemolytic workup autoimmune chronic hemolysis syndrome algorithm causes cll leukemia lymphocytic mds monoclonal myelodysplastic aclf activation acute aiha
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic Anemia ... - Differential Diagnosis ... Agglutinin Disease ... #Differential #Diagnosis ... #Table #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... anemia • Cold ... test #cold # ... #hematology #diagnosis
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
, C3d ( +/- ) Cold ... agglutinin disease ... #antiglobulin #test ... Autoimmune #Hemolysis #hematology ... #diagnosis
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Spherocytes • Treatment ... transient hemolysis • Treatment ... BostonChiefs #Warm #Cold ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
: 70 years old, ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... agglutin disease ... #hematology #anemia
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency Anemia ... (IDA) Tests: ... Iron #Deficiency #Anemia ... #Fe #diagnosis # ... hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Agglutination - Cold ... agglutinins disease ... Algorithm #workup #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Autoimmune: Warm AIHA, Cold ... Defects: Sickle cell anemia ... Laboratory Tests ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... practices that could ... K), H. pylori test ... changes), high MCV anemia ... Causes #Workup #hematology
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