37 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
: 70 years old, ... cytopenias (usually anemia ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Warm vs Cold Autoimmune ... Spherocytes • Treatment ... transient hemolysis • Treatment ... BostonChiefs #Warm #Cold ... #hematology #diagnosis
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Hemolysis #Hemolytic #Anemia ... Causes #Workup #Hematology ... #Diagnosis * ... GrepMed Recommended Text
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... anemiaCold ... Test: Donath-Landsteiner ... test #cold # ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... • Neutropenia, anemia ... microglobulin Treatment ... #workup #oncology ... #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Agglutinate: Cold ... , Paroxysmal cold ... #differential #diagnosis ... #hematology #microscopy
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) (e.g. lupus, CLL ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... #hematology #anemia
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Diagnosis: • Pancytopenia ... Treatment: • Consider ... stem cell transplant ... #diagnosis #management ... #treatment #hematology
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency Anemia ... (IDA) Tests: ... Iron #Deficiency #Anemia ... #Fe #diagnosis # ... hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... - infiltrates (anemia ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis