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rheumatology symptoms erythematosus sle allergy differential hypersensitivity pathophysiology reactions syndrome vasculitis allergic criteria cryoglobulinemia cryoglobulins definitions dermatology disease emergency eularacr
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
complexes • Ex: Systemic ... Lupus Erythematosus ... , Reactive Arthritis ... #Classification ... #Diagnosis #Definitions
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Clinical Domains ... • Arthritis domain ... #diagnosis #rheumatology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... glomerulonephritis, rheumatoid arthritis ... , and systemic lupus ... #Classification ... Pathophysiology #Allergy #Diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Syndrome: • Clinical ... Labs/Diagnosis: ... lupus erythematosus ... #types #classification
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... like rheumatoid arthritis ... lupus erythematosus ... (SLE) Signs / ... Pathophysiology #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Skin Disease Classification ... Differential Diagnosis ... Kikuchi disease • Type-I
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... such as certain types ... ’s syndrome - Lupus ... Leukemia cutis Diagnosis ... Sweet #Syndrome #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... inflammation Others: • Lupus ... lupus erythematosus ... purpura: strong sign ... #rheumatology #classification
Emergent Causes of Headache and Associated Risk Factors Carbon monoxide poisoning - Breathing in enclosed or confined
febrile illness—any type ... immunization Temporal arteritis ... lupus) - Previous ... headache #redflags #signs ... differential #emergency #diagnosis
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