14 results
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... volume-based algorithm Urine ... restriction alone in SIADH ... , Renal Sodium loss ... #nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Utilizing Uric Acid ADH ... Sodium 4) Serum ... Low Uric Acid → SIADH ... Diagnosis #Algorithm #nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) Sodium ... Hypovolaemia → ADH ... → Increased urine ... Pathophysiology #diagnosis #nephrology ... #hyponatremia #
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... treat underlying cause ... , SSRIs) - SIADH ... Algorithm #diagnosis #nephrology ... #sodium
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... • Reduced GFR, AKI ... Hypo-osmolar urine ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... • Reduced GFR, AKI ... Hypo-osmolar urine ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
among the possible causes ... in blood urea causes ... Measured urine sodium ... #hyponatremia #ADH ... EBV #potomania #SIADH
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
promoting passive sodium ... Saline: • If Urine ... antagonists: • Blocks ADH ... #Management #hyponatremia ... #nephrology #treatment
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
promoting passive sodium ... 0.9% NS • If Urine ... vaptans) • Blocks ADH ... #Management #hyponatremia ... #nephrology #treatment
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... fragmentocytes, LDH ... Differential #Diagnosis #nephrology ... #causes