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diagnosis erythematosus systemic activation antiil6 atopic dermatitis dermatology differential druginduced drugs hcq hydroxychloroquine macrophage mas measurement risk serum siltuximab summary
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... 200ng/mL Best indications ... #rheumatology # ... pharmacology #levels ... #lupus #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Hydroxychloroquine *Short ... #Systemic #Lupus ... Summary #diagnosis #rheumatology ... #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... antibodies, Complement levels ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19 IL-6 activates T cells and macrophages, among other cell types (see
Siltuximab) in COVID19 ... other cell types (see ... Syndrome” IL-6 levels ... #Pharmacology # ... Management #Medications
Atopic Dermatitis - Topical Treatment Options First Line: Topical Corticosteroids - High Potency: Betamethasone
After non-pharmacologic ... has a different level ... than roflumilast (see ... #Pharmacology # ... Dermatology #Management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SJIA], systemic lupus ... erythematosus [SLE ... ALT ↑ bilirubin level ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Induced Systemic Lupus ... with drug-induced SLE ... Erythematosus #medications ... #drugs #pharmacology ... differential #diagnosis #rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... immunoglobulin levels ... TAFRO #diagnosis #management ... #rheumatology #
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