41 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... Hyperviscosity Syndrome ... Hoarseness • Chest and ... shoulder pain, ... #differential #diagnosis
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
carotid sinus syndrome ... The diagnostic approach ... Further diagnostics ... should be guided ... The treatment strategy
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
predispose to other orthopedic ... common sites: hip, shoulder ... XR, MRI to dx and ... #differential #diagnosis ... #causes #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
Orthopedic Emergencies ... affected part should ... • Syndrome caused ... • Diagnosis: ... #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... #management #hematology ... #oncology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... normal in mild cases ... athletic regimens should ... #Management #treatment ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
- Differential Diagnosis ... - Ramsay Hunt syndrome ... Temporal arteritis should ... Otalgia #Ear #Pain #Otology ... #differential #diagnosis