19 results
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Wiskott-Aldrich syndrome ... telomeropathy Cancer ... Systemic lupus erythematosus ... Differential #Diagnosis #Hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment ... Summary #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Shrinking lung syndrome ... leukemia • Lung cancer ... • Cervical cancer ... #Diagnosis #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... Puncture, EEG Treatment ... Systemic #Lupus #Erythematosus ... CNS #neurology #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS
Venous Thrombosis - Arterial Thrombosis
INR Target
Duration
Recurrence

Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... Antiphospholipid #Syndrome ... management #EULAR2019 #guidelines ... #rheumatology # ... hematology #treatment
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... adsorption onto cancer ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... Systemic lupus erythematosus ... Other Causes: Cancer ... Differential #Diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Systemic lupus erythematosus ... systemic lupus erythematosus ... Treatment: • Corticosteroids ... #Rheumatology
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Gastroenteritis: Treatment ... strictures Severe + Concern ... for HES: • Hematology ... Gastroenteritis #Treatment ... #management #gastroenterology