12 results
Osteoblastic Metastases on Chest XRay

Dr. Devpriyo Pal @drdevrad

#Osteoblastic #Metastases #Chest #XRay #CXR #clinical #radiology #labeled
Osteoblastic Metastases ... Pal @drdevrad #Osteoblastic
Causes of Hypocalcemia - Differential Diagnosis Algorithm
 • Extravascular: Pancreatitis, surgery, acute phosphate intake and renal
renal failure, Osteoblastic
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
production of osteoblasts ... and GF's -> Osteoblasts
Hypocalcemia Workup - Differential Diagnosis Algorithm
 • Low Magnesium, High Magnesium - Functional Hypoparathyroidism
 • High
Pancreatitis, Sepsis, Osteoblastic
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
cartilaginous matrix by osteoblasts ... • Osteoclast-osteoblast ... gentamycin - Toxic to osteoblasts
Bone resorption and the relationship between osteoblasts and osteoclasts.  
RANK is expressed on the osteoclasts,
relationship between osteoblasts ... marrow cells and osteoblasts ... Endocrinology #Osteoblasts
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
syndrome) - Osteoblastic
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
bone syndrome), Osteoblastic
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
IGFIR activates osteoblasts
Malignant Bone Tumors: Pathogenesis of X-ray appearance

 • Metastatic bone tumors (aka. cancerous cells from systemic
cells activate osteoblasts