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diagnosis symptoms signs management differential pharmacology cardiology endocrinology nephrology syndrome infectiousdiseases complications msk causes ophthalmology parasite algorithm cdc hematology hepatology
Bone resorption and the relationship between osteoblasts and osteoclasts. RANK is expressed on the osteoclasts,
relationship between osteoblasts ... and osteoclasts ... expressed on the osteoclasts ... RANK stimulates osteoclast ... #Pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
production of osteoblasts ... and GF's -> Osteoblasts ... expression of osteoclasts ... -> Incr Osteoclasts ... #Osteoporosis #pathophysiology
COVID-19 Life Cycle #COVID19 #LifeCycle #Timeline #Pathophysiology #Diagnosis
Cycle #COVID19 #LifeCycle ... #Timeline #Pathophysiology
Malignant Bone Tumors: Pathogenesis of X-ray appearance • Metastatic bone tumors (aka. cancerous cells from systemic
cells activate osteoblasts ... more than osteoclasts ... activate largely osteoclasts
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
IGFIR activates osteoblasts ... endocrinology #pathophysiology
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
cartilaginous matrix by osteoblasts ... mos - yrs) • Osteoclast-osteoblast ... gentamycin - Toxic to osteoblasts ... #msk #Staging #pathophysiology
Leishmaniasis Life Cycle 1) Sandfly takes a blood meal (injects promastigote stage into the skin) Human Stages: 2) Promastigotes
Leishmaniasis #LifeCycle ... #diagnosis #pathophysiology
Diabetes Pathophysiology and Medication Targets The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology
Causes of Hypocalcemia - Differential Diagnosis Algorithm • Extravascular: Pancreatitis, surgery, acute phosphate intake and renal
renal failure, Osteoblastic
Hypocalcemia Workup - Differential Diagnosis Algorithm • Low Magnesium, High Magnesium - Functional Hypoparathyroidism • High
Pancreatitis, Sepsis, Osteoblastic
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