359 results
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing ... Stage (0-7d) • Fracture ... cartilaginous matrix by osteoblasts ... mos - yrs) • Osteoclast-osteoblast ... gentamycin - Toxic to osteoblasts
Bone resorption and the relationship between osteoblasts and osteoclasts.  
RANK is expressed on the osteoclasts,
relationship between osteoblasts ... and osteoclasts ... expressed on the osteoclasts ... RANK stimulates osteoclast ... #Osteoclasts #Bone
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS) Fracture ... Osteoporosis - Increased osteoclast
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
production of osteoblasts ... and GF's -> Osteoblasts ... expression of osteoclasts ... -> Incr Osteoclasts
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Complications Abnormal Osteoclasts ... -> Pathologic fractures
Unstable Cervical Spine Fractures 
The common mnemonic “Jefferson Bit Off A Hangman’s Thumb,” is used to
Cervical Spine Fractures ... Jeffereson Fracture ... AKA C1 Burst Fracture ... 2 & 3 C2 Dens Fracture ... Teardrop Fracture
Common Hand Fractures on X-Ray
Mallet finger - injury to the lateral extensor slips
Boutonniere deformity - injury
Common Hand Fractures ... ligament Bennet fracture ... Rolando fracture ... Scaphoid fracture ... Boxer's fracture
Classification of Hip Fracture According to Anatomical Fracture Site. Hip fractures are anatomically classified in relation
Classification of Hip Fracture ... to Anatomical Fracture ... Hip fractures are ... Femoral-neck fractures ... Fractures below
Malignant Bone Tumors: Pathogenesis of X-ray appearance

 • Metastatic bone tumors (aka. cancerous cells from systemic
cells activate osteoblasts ... more than osteoclasts ... activate largely osteoclasts
Odontoid Fractures 
Type I  [Stable]  - Avulsion of the tip 
Type II [Unstable] -
Odontoid Fractures ... II [Unstable] - Fracture ... Ill [Unstable] - Fracture ... #Odontoid #Fractures