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Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
Osteoporosis: Pathogenesis ... Hyperthyroid #Osteoporosis ... pathophysiology #signs
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Glucocorticoid-Induced Osteoporosis ... Glucocorticoids #steroids #Osteoporosis ... pathophysiology #signs
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
bone infarcts, osteoporosis ... Disease #Diagnosis #Signs
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
suspected: • Signs ... discernable cause • Signs ... of osteoporosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Normal CK • Osteoporosis ... pathophysiology #signs
Short Bowel Syndrome - Acute and Chronic Adverse Signs and Symptoms of Ileal Resection • Dehydration
Chronic Adverse Signs ... Bone Disease, Osteoporosis ... ShortBowel #Syndrome #Signs
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... Fragile bones/osteoporosis
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... mineral density and osteoporosis
Celiac Disease - Clinical Manifestations Gastrointestinal Manifestations: • Diarrhea, Loose stools, Dyspepsia, Flatulence, Chronic abdominal pain,
Arthritis, Osteopenia, Osteoporosis ... Celiac #Disease #signs
Clinical Feature of Hypomagnesemia and Magnesium Deficiency • Electrolyte Disturbance: Hypokalemia, Hypocalcemia • Neuromuscular and central
Myocardial infarction, Osteoporosis ... Hypomagnesemia #diagnosis #signs
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