10 results
Approach to Emergency Management of Hyponatremia
- Dr. Edward Etchells

#Management #Emergency #Hyponatremia #Algorithm #Overcorrection #DDAVP
Hyponatremia #Algorithm #Overcorrection ... #DDAVP
Causes of Polyuria - Differential Diagnosis Algorithm
Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min)
Osmotic
Excessive Loss - DDAVP ... Insipidus - DDAVP
Outcomes in Severe Hyponatremia Treated With and Without Desmopressin.

Am J Med. 2018 Mar;131(3):317.e1-317.e10. doi: 10.1016/j.amjmed.2017.09.048. Epub
#Desmopressin #DDAVP
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Overcorrection of
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Desmopressin (DDAVP
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
Treatment: Platelets, DDAVP
Hypertonic Saline for Treatment of Hyponatremic Encephalopathy
1) 100 ml bolus of 3% NaCl over 10 min.
therapeutically re-lower overcorrection
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
augmentation with DDAVP
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Desmopressin (DDAVP
DDAVP Clamp Protocol in Hyponatremia
 • Stop any maintenance fluids.
 • Start DDAVP 2 mcg IV
DDAVP Clamp Protocol ... • Start DDAVP ... Continue 3% and DDAVP ... sodium is 125-130 #DDAVP